The Santa María Hotel & Golf Resort is the only urban resort in the most cosmopolitan city of Central America, Panama City. The hotel's interior design balances the history and culture of Panama. With beautifully crafted furniture, including its shelves and wooden columns inspired by the square trees of Anton Valley, a Panamanian town located in the crater of an extinct volcano, The Santa María has a unique and distinctive character. At The Santa María Hotel & Golf Resort, our guests enjoy of luxurious assigned rooms and suites and have access to our exclusive amenities and recreation areas, where they will be provided with an outstanding service every step of the way.